Serum drops—the last resort for topical treatment after refractive surgery and laser in situ keratomileusis-induced neuropathic epitheliopathy (LINE)

Introduction: The idea to apply blood or product topical treatment is not new in ophthalmology, but about 40 years ago Ralph was the first publish this idea. biochemical properties of serum eye drops are very similar water component tears. Serum contains several growth factors, including epidermal factor, transforming factor-β and platelet-derived nutrients proteins, all which key components for tissue regeneration. Aim: aim article set a prospective study order identify follow patients with laser situ keratomileusis ( LASIK)-induced neuropathic epitheliopathy (LINE) analyze benefits application 20% autologous drops. Materials Methods: A total 16 subjects (10 females 6 males) at mean age 34 (19 youngest 41 oldest) were recruited prospectively. All seeking second opinion as they bothered by discomfort, visual fluctuations, chronic red eye, pain different characteristics. Each patient advised have week wash-out period when only non-preserved artificial tears (Hyabak 0.15%, Thea ®) applied. Then four times (during day), assessment done on 4th 8th week. primary outcome parameters ocular surface disease index (OSDI), tear break-up time (TBUT) corneal staining, secondary included acuity redness. Preparation followed in-house methodology. Results: significantly affected their underdiagnosed condition. Statistical analysis demonstrated that did change significantly. main parameter OSDI presented highest improvement from 57 ± 12 after 8 weeks Corneal staining decreased TBUT improved subjects. Conclusion: Epithelial complications LASIK uncommon recognition step long-term satisfaction refractive procedures. After diagnosis LINE LASIK, especially microkeratome, an efficient solution. standard usually takes achieve good results.